Inconclusive PGS
I just got the results of my PGS. Out of 8 d5 embryos, 4 abnormal, 2 inconclusive and 2 normal. Has anyone had an inconclusive result before? Did you retest? Thanks for any advice!
Kay, it’s incredibly frustrating! My doctor wasn’t sure if I should transfer at the end of March bc I was slightly over stimulated and he said it would depend on the PGS. If I had several good embryos he would be comfortable doing the transfer and if only a couple then I should wait. This information doesn’t help much...
I was told by the embryologist that inconclusive is a situation where the few cells they pulled included normal and abnormal cells. So it’s inconclusive because they don’t know if they pulled the one random abnormal cell in your cluster of 100+ in an embryo or if ALL the rest of the cells in the Blast are bad except for the ONE good cell they pulled along with the bad in a matter of speaking.
So I would say you have a 50/50 chance it’s still viable. (Not scientific) The cells they pull for testing are the tropectoderm cells that will eventually make the placenta. These CAN result in an healthy pregnancy as the body can sometimes repair these one off anomalies. So it’s really a matter determining the pros and cons of being more assured the embryo is good/cost of a failed frozen transfer vs the cost and expense of a new IVF cycle if you’re out of viable eggs.
As far as retesting, I know my clinic, Kaiser, will not transfer any “bad” embryos. So I would not retest if I still wanted a choice whether or not I wanted to transfer it anyway.
Hope this helps. ?
L, thanks that makes sense.
SJ, thank you that’s good to know