With my son, I felt a little nauseous and threw up once. With my daughter, I was nauseous 24/7, couldn't eat, and threw up every other morning. It was a huge difference for me in the first trimester at least.
I have two boys and they were night and day lol I was skinny, energetic (for being pregnant), and so happy with my first son and the second was opposite! Gained a lot of weight, tired, moody, and in pain. My daughter I was happy and no pain but gained a lot.