Have posted in a while, my little boy has been very off today,sleeping when he's cuddled but if you…

Have posted in a while, my little boy has been very off today,sleeping when he's cuddled but if you try and lay/sit him down he screams and crys frantically, has only drank 4oz in 10 hours which isn't like him. It's been going on for 14 hours and I'm exhausted,any advice