What is the most annoying pregnancy symptom you have/had ? Mine is the constant stuffy nose. I know I'm only suppose to use saline nose spray but it doesn't work for me and the only thing that does work is Regular nose spray. I haven't had a full night sleep in over a month thanks to always waking up stuffy and not being able to breathe. It's extremely uncomfortable and I've tried everything like using a vapor , propping my head up higher, using Vaseline, yet regular nose spray is the only thing that gives me relief. It's a pain in my butt !