We're on Enfamil nutramigen. My son has an allergy to cows milk. Nutramigen makes him spit up more but the others by Enfamil dont. he used the reg infant, the newborn and the gentlease with no spit up issues.
Our daughter used Similac Sensitive for lactose sensitive babies. she had tried Gerber Good Start Soothe and Gentle, also tried Enfamil A.R, Gentlease, Sobee but neither worked for her then we switched to Similac Advance and that didn't work for her either. The Similac for Spit up and Similac Sensitive was the only thing that helped her. Like previous poster said all depends on your baby and what they can handle.
Since i was 5 my grandma had a daycare and i would always help her with the babys and ive seen how more babys had less gas spit up etc with enfamil especially since they have different ones with in the brand now. Like one baby would spit up constantly and my grandma told her mom to change her to enfamil and she started to spit up less. But ive seen it go both ways thats why i said it really depends on your baby cause she/he could be allergic gassy etc