It's annoying when I want to just sit at my desk and work and a person that loves to talk keeps asking me questions just…

It's annoying when I want to just sit at my desk and work and a person that loves to talk keeps asking me questions just to hear my voice or something. Like. Leave me alone please before I lose my mind, if I have in headphones don't talk to me..if I'm looking at my computer screen..don't talk to me. If I have my eyes closed..don't talk to me ..if I'm eating (ESPECIALLY) don't talk to me