yes..its a difference. my son was in NICU and the whole time he was there he got breastmilk and the ready to feed formula. ...once he came home prepared the formula and it made him upset and he started having diarrhea and he didn't wanted to drink it, it was as if it was causing him pain...then there was blood accompanied in his loose stools....turns out theres one ingredient in the powder formula that he was allergic to, and the ready to feed didn't had it..even though itbws the same one....and he was already on that particular formula because he had milk protein allergy. so it does makes a difference

My son did great on both the premade liquid and the powder Gerber Good Start Gentle formula. Definitely ask your child's doctor about the situation. My son was also jaundiced after coming home. The nurse did a home visit and she said it would go away in a few days and it did. Good luck.

if she's starting to look like she may have jaundice then it's not the formula, it's her liver. take her to the ER or her dr tomorrow